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Bmp products such as Fig are persistent pollutants that accu
2019-08-23

Bmp7 products, such as 7–9 (Fig. 2), are persistent pollutants that accumulate in the marine environment and can potentially be transferred to the human population via our trophic connections to the oceans (Wan et al., 2009). In addition to potentially addressing the mechanistic curiosities describe
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Compounds and were outliers for this equation being
2019-08-23

Compounds and were outliers for this equation being the two most reactive compounds. The presence of outliers implies that other factors or specific mechanisms are involved in their chemical hydrolysis. Generally urea derivatives prove to be highly stable in aqueous solutions in vitro. Additional
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Michel et al calculated the mutual
2019-08-23

Michel et al. [34] calculated the mutual solubilities of water and hydrocarbons by a cubic equation of state. They asserted that conventional mixing rules can not satisfactorily describe the hydrogen bonding compounds. Kabadi and Danner [35] applied a modified form of Soave-Redlich-Kwong equation of
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Although the control group and tinnitus group do
2019-08-23

Although the control group and tinnitus group do not significantly differ based on age, gender or hearing loss, a limitation of this study is that the control group is only group-matched, and not individually matched. Furthermore, we only tested hearing acuity in tinnitus patients via standard pure
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Introduction br CK in the Regulation of Hh
2019-08-23

Introduction CK1 in the Regulation of Hh Pathway CK1 was initially identified as a negative regulator of Hh signaling at the level of transcription factor Ci by genetic studies in Drosophila and genome-wide RNAi screen in Drosophila cultured Tirapazamine (Jia et al., 2005, Lum et al., 2003, Pri
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Introduction Hepatocarcinoma is a common and aggressive form
2019-08-23

Introduction Hepatocarcinoma is a common and aggressive form of cancer (Trad et al., 2017). Due to a high rate of postoperative recurrence and metastasis, the prognosis for HCC remains dismal (Wang et al., 2017a, 2017b). Subclinical metastasis is the major cause responsible for tumor recurrence and
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br Conclusions br Statement of authorship br Nonaneurysmal s
2019-08-23

Conclusions Statement of authorship Nonaneurysmal subarachnoid hemorrhage (NA-SAH) differs from aneurysmal subarachnoid hemorrhage (SAH) in both clinical course and outcome. In spite of many reports and case series since the first description in 1985, the etiology of NA-SAH remains uncertain
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The presence of a vicious cycle established between tumor
2019-08-23

The presence of a “vicious cycle” established between tumor proliferation and paratumor osteolysis plays a crucial role in the development of primary bone tumors [53]. Cancer cells produce soluble factors that activate directly or indirectly via osteoblasts, osteoclast differentiation and maturation
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br Synthesis and mechanism of fluorescent DNA CuNMs br
2019-08-22

Synthesis and mechanism of fluorescent DNA-CuNMs Application of fluorescent DNA-CuNMs Summary and conclusions In summary, we introduce recent research progress in the synthesis and various applications of DNA-CuNMs. DNA-CuNMs with novel catalytic, electrical and optical properties can be ob
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The larger eukaryotic ligases such as LigI and LigIV
2019-08-22

The larger eukaryotic ligases, such as LigI and LigIV, also possess an additional N-terminal DNA-binding domain (DBD) that is required for efficient ligation (Fig. 1c) and enables these ligases to encircle DNA [17]. An equivalent helix–hairpin–helix domain is also present in the bacterial NAD-depend
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QSAR based on the D structures of ligands plays an
2019-08-22

QSAR based on the 3D structures of ligands plays an important role in the ligand-based drug discovery and design [12]. Comparative molecular field analysis, CoMFA [11], and comparative molecular similarity index analysis, CoMSIA [12] are among the most popular QSAR models. They focus on changes in 3
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The intestinal cholesterol absorption markers sitosterol and
2019-08-22

The intestinal cholesterol pten inhibitor markers sitosterol and campesterol to cholesterol levels were significantly lower in Villin-Tgif1 mice compared to wild type mice, irrespective of diet. However, the decrease was less pronounced in Villin-Tgif1 mice fed a chow diet (∼20–30%) compared to mic
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br Acknowledgements This work was supported in part
2019-08-22

Acknowledgements This work was supported in part by JSPS KAKENHI Grant Number 26292031. Introduction The Cys-loop receptors constitute an important superfamily of ligand-gated ion p53 tumor suppressor (LGICs) and mediate synaptic transmission in both invertebrate and vertebrate nervous system
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With this we find This is all that one
2019-08-22

With this we find This is all that one can say for , however when there is also a negative CID 2745687 manufacturer solution which is a bound state. One must have in this case, up to a normalization constantwith K>0. The delta potential now imposes or and one has as the energy of the bound state.
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The combination of brequinar and fluorouracil
2019-08-22

The combination of brequinar and 5-fluorouracil (5-FU) has been evaluated to assess whether brequinar-induced uridine depletion would improve 5-FU activity. In cells, 5-FU is metabolized into FdUMP and inhibits thymidylate synthetase, which catalyzes the formation of thymidine monophosphate from deo
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