• There are conflicting studies on ET axis and

  2019-11-14

  

  There are conflicting studies on ET axis and its relationship with clinicopathologic parameters in various cancers. Endothelin axis expression in the tissue and in blood has been associated with advanced cancer characteristics in colorectal, breast, and prostate cancer, while showing no linkage to c

• Despite a high affinity for progesterone and a relatively

  2019-11-14

  

  Despite a high affinity for progesterone and a relatively high affinity for testosterone [7], the binding of progesterone and testosterone to CBG is often disregarded [1], [2], [3]. However, the concentrations of these two hormones varies considerably under both normal physiological and pathophysiol

• br Acknowledgments br Introduction Ubiquitin ligases limit t

  2019-11-14

  

  Acknowledgments Introduction Ubiquitin ligases limit the stability and activity of substrates by targeting them for proteasomal-dependent degradation. Siah is a two-member family of ubiquitin ligases implicated in control of key cellular processes. Among those, Siah ligases control prolyl hydr

• Addressing whether impaired activation of

  2019-11-14

  

  Addressing whether impaired activation of D1 and D2 receptors regulates memory capacity is relevant for all human pathologies that lead to reduced activation of these cathepsin g pathways, such as ageing [39], certain genetic polymorphisms [40] and neurodegenerative disorders. In this study, we hav

• br Materials and methods br Results

  2019-11-13

  

  Materials and methods Results Discussion The investigation of oxysterols is highly complex and challenging, arising not only from the large number of molecules in this family, but also due to their low abundance in biological systems compared to cholesterol and their susceptibility for auto

• Addressing whether impaired activation of D

  2019-11-13

  

  Addressing whether impaired activation of D1 and D2 receptors regulates memory capacity is relevant for all human pathologies that lead to reduced activation of these Digoxigenin-11-dUTP receptor pathways, such as ageing [39], certain genetic polymorphisms [40] and neurodegenerative disorders. In t

• Bromfenac Sodium australia br Casein Kinase II CK Casein Kin

  2019-11-13

  

  Casein Kinase II (CK2) Casein Kinase II (CK2) is a ubiquitous serine/threonine-selective pro-oncogenic protein kinase that has become a more prominent target for research due to its effects and key role in tumorigenesis (Gowda et al., 2017a, Pinna, 2002). CK2, a well-conserved, pleiotropic kinase

• Many studies have shown that curcumin delays the progression

  2019-11-13

  

  Many studies have shown that curcumin delays the progression of atherosclerosis in different atherosclerotic animal models [18], [19], [20], [37] and the risk of atherosclerosis in human studies [15], [38], [39]. Curcumin also has many properties that contribute to combat atherosclerosis, such as an

• The CLC proteins in Arabidopsis have been studied in some

  2019-11-13

  

  The CLC proteins in Arabidopsis have been studied in some detail, and a total of seven genes (named AtCLCa-AtCLCg) have been identified (Lv et al., 2009). It is interesting that AtCLCa-AtCLCd and AtCLCg define a distinct phylogenetic branch that is closely related to eukaryotic CLCs, while the other

• br Conclusion To our knowledge this study is the first

  2019-11-13

  

  Conclusion To our knowledge, this study is the first to give evidence that the ETA selective antagonist BQ-123 reverses the cisplatin-induced ARF mainly via restoring SOD activity, in addition to other antioxidant parameters, NO, TNF-α and caspase-3 levels. And that this protective effect require

• br Thy nephritis is one of

  2019-11-13

  

  Thy1.1 nephritis is one of the most commonly used models to study the course of immunoglobulin A and other mesangioproliferative nephropathies. To date, most of the studies have focused on mesangial and, to a lesser extent, endothelial cell recovery following capillary damage, whereas data concer

• The ultrafiltration approach has been used to measure equili

  2019-11-13

  

  The ultrafiltration approach has been used to measure equilibrium BIEs for a number of enzyme systems, including nonreceptor tyrosine kinase hexokinase (Lewis and Schramm, 2003a, Lewis and Schramm, 2003b), thymidine phosphorylase (Birck & Schramm, 2004), purine nucleoside phosphorylase (Murkin, Tyl

• A factor that complicates the

  2019-11-13

  

  A factor that complicates the use of human liver d-amphetamine is one of variability, which arises in part because many of the human liver samples available for research show various stages of a variety of disease states (steatosis (fatty liver), cirrhosis, carcinogenesis in adjacent tissue), altho

• Mulan is a mitochondrial protein and

  2019-11-13

  

  Mulan is a mitochondrial protein and is exclusively localized in the OMM with its RING domain facing the cytosol [14]. Based on this topology, Mulan can provide a link between molecular events in the mitochondria and cytoplasm. Mulan has been implicated in various processes including: mitochondrial

• hnRNP E functions in a number of mRNA regulatory processes

  2019-11-13

  

  hnRNP E1 functions in a number of mRNA regulatory processes including transcription [74], [75], splicing [7], [74], [76], [77] and translation [6], [8], [69], [78], interacting with RNAs through CU rich regions such as the differentiation control element (DICE) and the TGFβ activated translation (BA

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