• br Conclusions br Conflicts of

  2024-04-08

  

  Conclusions Conflicts of interest Acknowledgements This work was supported by Ege University Research Fund [BAP, 14-ECZ-030, 2016]. Introduction The interest in the effects of endocrine disrupting chemicals (EDCs) in the aquatic environment continues to increase over the past decade, sp

• The first description of autophagy

  2024-04-08

  

  The first description of autophagy as a tumour suppression process arises from the observation that the initial step regulatory gene, Atg6/BECN1, was monoallelically lost in 40% to 75% of human prostate, breast, and ovarian cancers [31]. However, while BECN1 heterozygous mutant mice develop, with lo

• Herbal medicines have been used

  2024-04-07

  

  Herbal medicines have been used to treat various types of diseases and disorders for thousands of years worldwide (Li and Brown, 2009). Natural products have been the remedy of cancer chemotherapy for the past several decades. Anisomeles indica (L.) Kuntze. (Labiatae), commonly known as 'yu-chen-tsa

• Estrogen exerts its genomic action via estrogen nuclear

  2024-04-07

  

  Estrogen exerts its genomic action via Ertapenem sodium salt nuclear receptor: ERα and ERβ. The distribution of ERα and/or ERβ positive neurons in CNS of different species has been mapped extensively by various methods [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], although there are s

• Furthermore we also found that

  2024-04-07

  

  Furthermore, we also found that the basic level of ROS was markedly lower in mtDNA-reduced SW480 Varenicline Tartrate than that in the parent cells. Endogenous ROS is most notably produced at the sites of complex I and complex III [5], it might be plausible that the decreased quantity of ROS observ

• br Implications for cancer ROS

  2024-04-07

  

  Implications for cancer ROS have a long history of being involved in the development and progression of cancer and increased ROS level is considered as a hallmark of many tumors [76], [77]. Initially, it was thought that ROS would serve as chemical mutagens that would indiscriminately damage cel

• To better illustrate the involved neuronal postganglionic pa

  2024-04-07

  

  To better illustrate the involved neuronal postganglionic pathways, central apelin-13 injection was performed in rats received peripheral preadministration of NOS inhibitor L-NAME, sympatholytic agent guanethidine and/or muscarinic receptor agonist bethanechol. Compared with the rats received vehicl

• We conclude that Tetrapleura tetraptera fruits extract posse

  2024-04-07

  

  We conclude that Tetrapleura tetraptera fruits extract possess antiplasmodial activity and the results of this study justifies and confirms the traditional usage of this plant as malarial remedy. Acknowledgement Introduction The phylum apicomplexa comprises of nearly 5000 species, most of whi

• Unexpectedly under pathological pain conditions

  2024-04-07

  

  Unexpectedly, under pathological pain conditions, inhibition of spinal glutamate transporter activity can produce antinociceptive effects. For example, intrathecal injection of the transportable inhibitor trans-pyrrolidine-2,4-dicarboxylic AG 1879 (t-PDC) or antisense oligonucleotides reduced nocic

• br Experimental procedure br Funding The present study was s

  2024-04-07

  

  Experimental procedure Funding The present study was supported by the Grant Russian Foundation for basic research (project no. 16-04-01517). Introduction 5-HT, a monoaminergic neurotransmitter, is synthesised from l-tryptophan catalysed by the enzymes tryptophan hydroxylase (Tph) and aroma

• pyridoxal phosphate mg Actin is capable of polymerizing spon

  2024-04-07

  

  Actin is capable of polymerizing spontaneously. However, this process is relatively slow and kinetically unfavorable in cells. Formation of pyridoxal phosphate mg dimers and trimers, which can easily disassemble due to their instability, is a rate-determining step in actin polymerization [5], [6].

• br Perspectives Given the complexity of the cellular interac

  2024-04-03

  

  Perspectives Given the complexity of the cellular interactome and of protein scaffolding, further progress in revealing how individual membrane proteins, including APP and AChE, interact with each other at various levels, from cell-surface shedding to gene regulation, will clarify some intrinsic

• rs G allele was previously

  2024-04-03

  

  rs523349 G allele was previously associated with a decrease in the conversion rate of testosterone to DHT (Beesley et al., 2007). This SRDA52 variant may have a trend towards higher testosterone availability, which according to the US Food and Drug Administration is described as a teratogen of categ

• br The cytochrome P enzyme hydroxylase lyase P is involved

  2024-04-03

  

  The cytochrome P450 enzyme 17α-hydroxylase/17,20-lyase (P450) is involved in the production of the C containing androgen precursors from the C containing steroids such as the pregnanes and progestins (). Steroids such as androstenedione (AD) and dehydroepiandrosterone (DHEA) are therefore synthesi

• The first description of autophagy

  2024-04-03

  

  The first description of autophagy as a tumour suppression process arises from the observation that the initial step regulatory gene, Atg6/BECN1, was monoallelically lost in 40% to 75% of human prostate, breast, and ovarian cancers [31]. However, while BECN1 heterozygous mutant mice develop, with lo

15264 records 172/1018 page Previous Next First page 上5页 171172173174175 下5页 Last page